TAVR / TAVI Patents

Name: TavrPatents
Address: US

For Sale or License

Patents for improved guide wire management and patient outcomes

TAVR (transcatheter aortic valve replacement) is a $5B+ market today and projected to be over $10B by 2030. This minimally invasive technique offers several benefits, such as reduced hospital stay, faster recovery time, and improved patient outcomes. Even with the advancements in the technology, there are opportunities to improve.

Alignment of the prosthetic valve within native valve anatomy
Mitigate the unpredictability of the final prosthetic valve position during deployment
Incorporating patient specific 3D anatomical scans to design the ideal guide wire shape to facilitate optimal valve implantation
Simplify the learning curve for new implanting surgeons and cardiologists
Reducing the number of operators required for the procedure

The offered portfolio of patents addresses current and future TAVR challenges by focusing on improvements to guide wire shapes, management and selection. In addition to these patents improving TAVR outcomes, the technologies are potentially applicable to other structural heart procedures where precision is needed to overcome anatomical challenges. With a priority date of 01-25-2016, the core patent filing still has a pending child application and the ability to have new continuations filed.

Keep your competition from making, using or selling these technologies!

Priority date 1/2016
4 Issued US patents, one pending
New continuing applications possible
Ability to exclusively own the portfolio
Supports offensive or defensive strategies
Keep others from making, using or selling.

Highlights

Developed by a Cariodologist

Over 1,000 TAVR procedures

The technologies covered by the patents were developed by a leading cardiologist that has personally performed over 1000 TAVR procedures since 2011 using about equally the self-expanding and balloon expandible devices. Although current TAVR devices and operator experience has improved, there remains considerable opportunity to improve implant precision and patient outcomes. Believing in the value to patients, he invested his own time and money to create the technologies.

It's About the Guide Wire

TAVR is unique and challenging

TAVR/TAVI is unique in comparison to other cardiovascular catheter procedures in that the guide wire isn't a simple rail within a tubular structure and exact position within the tube is unimportant, but rather with TAVR the guidewire is an important component in the proper deployment of the prosthetic valve. The guide wire can alter location/depth and angle of the valve which influences patient outcomes. In addition, simultaneously managing the guide wire and valve deployment device is complex and challenging for practitioners. The technologies of the offered patents simplifies the procedure, improves locations accuracy and reduces the number of people required for a successful procedure.

Enabling the Future

Apparatus and methods

In addition to a device to enable practitioners to more accurately perform TAVR procedures today, the portfolio of patents provides methods to enable future improvements. Central to these technologies is the recognition that no two patient aortic anatomies are identical, yet the current state of the field is to utilize a single wire shape (straight with the exception of only the distal tip) for all patients. Through imaging, dimensional components of the heart and lumens can be scanned and optimal guide wire shapes can be selected or fabricated to further improve valve deployments, simplify procedures and improve patient outcomes. Importantly, these technologies can be translated to a host of other procedures (cardiac and beyond).

Patient Specific Guide Wires

US Patent No. 10,967,148

The method includes steps of scanning a patient's anatomy and then fabricating, or selecting, a guide wire with optimal geometry for a particular patient and/or procedure. The guide wire may optionally be secured to a guide wire control device for improved control during transcatheter surgical procedures.

View Patent

Integrated Guide wire Manager

US Patent No. 9,918,838

A rotating actuator controls the translation of the translating assembly and resulting guide wire. The guide wire control device provides improved control of guide wires and angles of a deployment capsule during transcatheter surgical procedures.

View Patent

Guide Wire Manager

US Patent No. 9,919,130

A guide wire control device and methods of use are described herein. A guide wire is retained by a lock mechanism to a sliding assembly. The sliding assembly controllably moves within a stationary assembly. The guide wire control device provides improved control of guide wires during transcatheter surgical procedures.

View Patent

Optimal Guide Wire Method

US Application 17/221,976 (Allowed)

1. A method of utilizing a guide wire for a surgical process which comprises:
(a) scanning a vascular lumen of a patient to generate an image;
(b) measuring said image to determine an optimal position of a prosthetic device relative to said vascular lumen;
(c) forming an internal end of a guide wire to have an optimized shape for aligning said prosthetic device to said optimal position; and,
(d) utilizing said guide wire as part of a surgical procedure to deploy said prosthetic device within said patient.

View Patent